New
Hyaluron-Filler

Eucerin Epicelline® Serum

  • 4.5
    160 reviews
Skin concerns
Aging skin
Key Benefits
  • Targets signs of aging
  • Leaves skin looking firmer
  • Reduce the appearance of wrinkles
  • Visible results in 4 weeks* *Based on a 2023 clinical study, 43 participants using twice-daily application for 4 weeks. Results may vary.
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Sustainability & Environment

We take responsibility. For your skin. And our planet.

Learn more about our sustainability program

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About

A clinically-tested epicellinic anti-aging serum based on Age-Clock® Technology: Epicelline®. This formula targets signs of aging for firmer and younger looking skin.
NART: 99122-05500-00

Read more about our product

Our breakthrough anti-aging innovation is here. Fine lines and wrinkles are accelerated by lifestyle and environmental factors that change the skin’s appearance. This means that more youthful genes are deactivated, leading to visible signs of aging. After 15 years of research, Eucerin has discovered that the Epicelline® enriched serum, based on Age-Clock® Technology, reduces the appearance of skin wrinkles and targets 10 signs of aging. The result? Visibly reduced fine lines, more hydrated skin with a lifted effect and enhanced contour. Plus, you’ll appear rejuvenated with a firmer, smoother and more radiant looking complexion.

Main findings

*Product-in-use test with 160 women over 4 weeks.
98% confirm:
reduces the appearance of wrinkles
99% confirm:
firmer-looking skin
98% confirm:
younger-looking skin
98% confirm:
rejuvenates the appearance of skin
99% confirm:
provides healthy-looking skin
97% confirm:
skin feels immediately hydrated

Clinical Formula

Hyaluronic acid
Hyaluronic Acid is formed by skin cells and is part of the connective tissue of the skin. One of its key functions is to retain moisture, and it has the ability to bind in between 1,000 and 10,000 times its own weight in water (i.e. one gram binds between one and ten liters). As we age, the skin's natural ability to produce Hyaluronic Acid depletes and wrinkles start to form and deepen.
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Glycine Saponin

Soy-derived bio-active Glycine-Saponin is proven as one of the most effective substances for stimulating natural Hyaluronic Acid production in the skin. It stimulates fibroblasts, the skin cells responsible for dermal Hyaluronic Acid production, to boost synthesis of new Hyaluronic Acid by up to 256% (in vitro).

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4.5
from 160 Reviews
Write Review
    2025-04-08
    A lovely serum
    [This review was collected as part of a promotion.] I have enjoyed using Eucerin Hyaluron-Filler Epigenetic Serum. The texture is lightweight and absorbs rapidly without leaving any residue. It provides a lovely boost of hydration to my skin, making it feel smoother and revitalized. I also appreciate how well it layers under moisturizer and makeup. Overall, it has been a wonderful enhancement to my skincare routine! As for the packaging, the glass bottle feels premium and looks stunning. The fragrance is subtle and fresh, not at all overwhelming, which I truly value in skincare products.
    emmac298_8556

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Key Ingredients

Epicelline, Hyaluronic acid, Glycine Saponin

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Size
30 ml
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    [This review was collected as part of a promotion.] Beautiful product. Does what it says I have enjoyed using this and noticed a difference in my skin. It's more hydrated and I look less tired. The bottle is easy to use and looks very stylish and expensive
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    2025-03-05
    Stunning serum 💖
    [This review was collected as part of a promotion.] I’ve been using the Eucerin Hyaluron-Filler Epigenetic Serum, and I really like how it feels on my skin. The texture is lightweight and absorbs quickly without any stickiness. It gives my skin a nice boost of hydration, making it feel smoother and more refreshed. I also love that it layers well under moisturizer and makeup. So far, a really nice addition to my skincare routine! Packaging – the glass bottle feels high-quality and looks beautiful. The scent is very light and fresh, not overpowering at all, which I really appreciate in skincare products.
    bee_bee_1765
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